Natural Genetic Engineering and Natural Genome Editing, Volume 1178 (Annals of the New York Academy of Sciences)

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Nov 142015
 

Natural Genetic Engineering and Natural Genome Editing, Volume 1178 (Annals of the New York Academy of Sciences)

Natural Genetic Engineering and Natural Genome Editing, Volume 1178 (Annals of the New York Academy of Sciences)

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The recent literature on whole genome sequences provides abundant evidence for the action of natural genetic engineering in evolution. Discoveries about natural genetic engineering have coincided with rapid progress in our understanding of epigenetic control and RNA-directed chromatin formation. Special attention needs to be paid to the role of viruses and related so-called “parasitic” elements in the origin of genome formatting and natural genetic engineering capabilities especially the role of

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Creative Bioarray CRISPR/Cas9 System for iPS

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Nov 142015
 

Creative Bioarray CRISPR/Cas9 System for iPS

Creative Bioarray CRISPR/Cas9 System for iPS

CRISPR/Cas-9 is a new genomic editing system that has the potential to revolutionize basic biomedical research and, possibly, the treatment of genetic disease. The CRISPR/Cas9 system, consisting of a guide RNA (gRNA) and a Cas9 nuclease, allows researchers to create a RNA-guided site-specific DNA cleavage. Creative Bioarray is able to use the double strand break created to modify your target gene by inducing a permanent knock-out, conditional knock-out, point mutation, or insertion.More informat

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Targeted Genome Editing Using Site-Specific Nucleases: ZFNs, TALENs, and the CRISPR/Cas9 System

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Nov 142015
 

Targeted Genome Editing Using Site-Specific Nucleases: ZFNs, TALENs, and the CRISPR/Cas9 System

Targeted Genome Editing Using Site-Specific Nucleases: ZFNs, TALENs, and the CRISPR/Cas9 System

This book serves as an introduction to targeted genome editing, beginning with the background of this rapidly developing field and methods for generation of engineered nucleases. Applications of genome editing tools are then described in detail, in iPS cells and diverse organisms such as mice, rats, marine invertebrates, fish, frogs, and plants. Tools that are mentioned include zinc finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs), and CRISPR/Cas9, all of which h

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